Electrochemical Investigation of 2-Hydroxy-2-Methyl Propiophenone Sulphamethizole Azomethine Compound Derived From Sulpha Drug Employing Cyclic Voltammetry Technique

Volume 14, Issue 54, 2025 (April – June)


Research Article
Electrochemical Investigation of 2-Hydroxy-2-Methyl Propiophenone Sulphamethizole Azomethine Compound Derived From Sulpha Drug Employing Cyclic Voltammetry Technique
Ishwar Chand Balaee
Keywords: 2-Hydroxy-2-methyl Propiophenone sulphamethizole, Cyclic voltammetry, Glassy carbon electrode, Irreversible, Diffusion-controlled.
DOI:10.37273/chesci.cs022056061


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Abstract
The cyclic voltammetric behavior of newly synthesized Schiff base 2-Hydroxy-2-methyl Propiophenone sulphamethizole (HMPSMO) was investigated at glassy carbon electrode (GCE) in acetone and methanol solvents using phosphate buffer and Britton-Robinson (BR) buffer within various pH values. Under the experimental conditions the cyclic voltammograms of HMPSMO consist of an irreversible cathodic wave at different sweep rate, that follows a one-step, two-electron transfer, diffusion-controlled electrochemical process which are ascribed to the azomethine group (-CH=N-) being reduced to the amine group (-CH2-NH-). The effects of solvent, buffer, sweep rate and pH are also studied on CV variables. Additionally computed were the kinetic parameters, including the rate constant (K°f,h), diffusion coefficient (D01/2), and charge-transfer coefficient (αn).


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